Embion

2022 Oct 18

Structure of the proteolytic enzyme PAPP-A with the endogenous inhibitor stanniocalcin-2 reveals its inhibitory mechanism.

Kobberø SD, Gajhede M, Mirza OA, Kløverpris S, Kjær TR, Mikkelsen JH, Boesen T, Oxvig C

2022 Oct 14

Cryo-EM structure of the human NKCC1 transporter reveals mechanisms of ion coupling and specificity.

Neumann C, Rosenbaek LL, Flygaard RK, Habeck M, Karlsen JL, Wang Y, Lindorff-Larsen K, Gad HH, Hartmann R, Lyons JA, Fenton RA, Nissen P

2022 Jun 29

Structures and mechanism of the plant PIN-FORMED auxin transporter.

Ung KL, Winkler M, Schulz L, Kolb M, Janacek DP, Dedic E, Stokes DL, Hammes UZ, Pedersen BP

2022 May 31

Cryo-EM structures of human A2ML1 elucidate the protease-inhibitory mechanism of the A2M family.

Nielsen NS, Zarantonello A, Harwood SL, Jensen KT, Kjøge K, Thøgersen IB, Schauser L, Karlsen JL, Andersen GR, Enghild JJ

2022 Apr 13

Autoinhibition and regulation by phosphoinositides of ATP8B1, a human lipid flippase associated with intrahepatic cholestatic disorders.

Dieudonné T, Herrera SA, Laursen MJ, Lejeune M, Stock C, Slimani K, Jaxel C, Lyons JA, Montigny C, Pomorski TG, Nissen P, Lenoir G

2022 Jan 21

Structural Investigations of Full-Length Insulin Receptor Dynamics and Signalling.

Nielsen J, Brandt J, Boesen T, Hummelshøj T, Slaaby R, Schluckebier G, Nissen P

2021 Nov 24

High-resolution structure of native toxin A from Clostridioides difficile.

Aminzadeh A, Larsen CE, Boesen T, Jørgensen R

2021 May 20

Structuralbasisof substrate-independent phosphorylation in a P4-ATPase lipid flippase.

Timcenko M, Dieudonne T, Montigny C, Boesen T, Lyons JA, Lenoir G, Nissen P

2020 Aug 25

Tracing the In Vivo Fate of Nanoparticles with a "Non-Self" Biological Identity.

Mohammad-Beigi H, Scavenius C, Jensen PB, Kjaer-Sorensen K, Oxvig C, Boesen T, Enghild JJ, Sutherland DS, Hayashi Y

2020 Jun 15

Binding of a negative allosteric modulator and competitive antagonist can occur simultaneously at the ionotropic glutamate receptor GluA2.

Krintel C, Dorosz J, Larsen AH, Thorsen TS, Venskutonyt? R, Mirza O, Gajhede M, Boesen T, Kastrup JS

2020 Jul

Polymer-Lipid Hybrid Vesicles and Their Interaction with HepG2 Cells.

Brodszkij E, Westensee IN, Bertelsen M, Gal N, Boesen T, Städler B

2020 Jun 19

DNA flowerstructure co-localizes with human pathogens in infected macrophages.

Franch O, Gutiérrez-Corbo C, Domínguez-Asenjo B, Boesen T, Jensen PB, Nejsum LN, Keller JG, Nielsen SP, Singh PR, Jha RK, Nagaraja V, Balaña-Fouce R, Ho YP, Reguera RM, Knudsen BR

2020 Mar 13

Carbon dots-fed Shewanella oneidensis MR-1 for bioelectricity enhancement.

Yang C, Aslan H, Zhang P, Zhu S, Xiao Y, Chen L, Khan N, Boesen T, Wang Y, Liu Y, Wang L, Sun Y, Feng Y, Besenbacher F, Zhao F, Yu M

2020 Mar 9

Full-length human GLP-1 receptor structure without orthosteric ligands.

Wu F, Yang L, Hang K, Laursen M, Wu L, Han GW, Ren Q, Roed NK, Lin G, Hanson MA, Jiang H, Wang MW, Reedtz-Runge S, Song G, Stevens RC

2020 Feb 25

Differential Nanoparticle Sequestration by Macrophages and Scavenger Endothelial Cells Visualized in Vivo in Real-Time and at Ultrastructural Resolution.

Hayashi Y, Takamiya M, Jensen PB, Ojea-Jiménez I, Claude H, Antony C, Kjaer-Sorensen K, Grabher C, Boesen T, Gilliland D, Oxvig C, Strähle U, Weiss C

2019 Jul 1

Namdinator - automatic molecular dynamics flexible fitting of structural models into cryo-EM and crystallography experimental maps.

Kidmose RT, Juhl J, Nissen P, Boesen T, Karlsen JL, Pedersen BP

2019 Jul

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