Embion

2023 Nov 18

Activation and substrate specificity of the human P4-ATPase ATP8B1.

Dieudonné T, Kümmerer F, Laursen MJ, Stock C, Flygaard RK, Khalid S, Lenoir G, Lyons JA, Lindorff-Larsen K, Nissen P

2023

Sarkosyl differentially solubilizes patient-derived alpha-synuclein fibril strains.

Gram H, Theologidis V, Boesen T, Jensen PH

2023 Aug

T-cell derived extracellular vesicles prime macrophages for improved STING based cancer immunotherapy.

Hansen AS, Jensen LS, Gammelgaard KR, Ryttersgaard KG, Krapp C, Just J, Jønsson KL, Jensen PB, Boesen T, Johansen M, Etzerodt A, Deleuran BW, Jakobsen MR

2023 Jul 19

RNA target highlights in CASP15: Evaluation of predicted models by structure providers.

Kretsch RC, Andersen ES, Bujnicki JM, Chiu W, Das R, Luo B, Masquida B, McRae EKS, Schroeder GM, Su Z, Wedekind JE, Xu L, Zhang K, Zheludev IN, Moult J, Kryshtafovych A

2023 May 20

Tertiary structure of single-instant RNA molecule reveals folding landscape.

Liu J, McRae EKS, Zhang M, Geary C, Andersen ES, Ren G

2023 May 22

RNA origami scaffolds facilitate cryo-EM characterization of a Broccoli-Pepper aptamer FRET pair.

Sampedro Vallina N, McRae EKS, Hansen BK, Boussebayle A, Andersen ES

2022 Oct 18

Structure of the proteolytic enzyme PAPP-A with the endogenous inhibitor stanniocalcin-2 reveals its inhibitory mechanism.

Kobberø SD, Gajhede M, Mirza OA, Kløverpris S, Kjær TR, Mikkelsen JH, Boesen T, Oxvig C

2022 Oct 14

Cryo-EM structure of the human NKCC1 transporter reveals mechanisms of ion coupling and specificity.

Neumann C, Rosenbaek LL, Flygaard RK, Habeck M, Karlsen JL, Wang Y, Lindorff-Larsen K, Gad HH, Hartmann R, Lyons JA, Fenton RA, Nissen P

2022 Jun 29

Structures and mechanism of the plant PIN-FORMED auxin transporter.

Ung KL, Winkler M, Schulz L, Kolb M, Janacek DP, Dedic E, Stokes DL, Hammes UZ, Pedersen BP

2022 May 31

Cryo-EM structures of human A2ML1 elucidate the protease-inhibitory mechanism of the A2M family.

Nielsen NS, Zarantonello A, Harwood SL, Jensen KT, Kjøge K, Thøgersen IB, Schauser L, Karlsen JL, Andersen GR, Enghild JJ

2022 Apr 13

Autoinhibition and regulation by phosphoinositides of ATP8B1, a human lipid flippase associated with intrahepatic cholestatic disorders.

Dieudonné T, Herrera SA, Laursen MJ, Lejeune M, Stock C, Slimani K, Jaxel C, Lyons JA, Montigny C, Pomorski TG, Nissen P, Lenoir G

2022 Jan 21

Structural Investigations of Full-Length Insulin Receptor Dynamics and Signalling.

Nielsen J, Brandt J, Boesen T, Hummelshøj T, Slaaby R, Schluckebier G, Nissen P

2021 Nov 24

High-resolution structure of native toxin A from Clostridioides difficile.

Aminzadeh A, Larsen CE, Boesen T, Jørgensen R

2021 May 20

Structuralbasisof substrate-independent phosphorylation in a P4-ATPase lipid flippase.

Timcenko M, Dieudonne T, Montigny C, Boesen T, Lyons JA, Lenoir G, Nissen P

2020 Aug 25

Tracing the In Vivo Fate of Nanoparticles with a "Non-Self" Biological Identity.

Mohammad-Beigi H, Scavenius C, Jensen PB, Kjaer-Sorensen K, Oxvig C, Boesen T, Enghild JJ, Sutherland DS, Hayashi Y

2020 Jun 15

Binding of a negative allosteric modulator and competitive antagonist can occur simultaneously at the ionotropic glutamate receptor GluA2.

Krintel C, Dorosz J, Larsen AH, Thorsen TS, Venskutonyt? R, Mirza O, Gajhede M, Boesen T, Kastrup JS

2020 Jul

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